In today’s chemical development for pharmaceuticals, fine and specialty chemicals, the use of enabling technologies can offer an edge in a very competitive environment. The challenge is to ensure the development of safe, green and scalable processes at an early stage, and to deliver high quality processes for full scale manufacture. The use of fully controlled multiple reactor systems that offer rapid data analysis tools - temperature, heat flow, pH, turbidity, viscosity, gas uptake and evolution - can provide the chemist with the required data-rich experiments for state-of-the-art process development. As this reaction knowledge can be acquired in parallel, faster and better designed synthetic routes become a reality. This webinar will demonstrate the value of MultiMaxTM - a multiple reactor walk-up tool for synthetic chemists.
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Your online presenter, Dr. Dominique Hebrault, who gained his Ph.D. in Organic Synthesis, has over 10 years experience in process development in the pharmaceutical and chemical industries using automated laboratory tools. During this webinar, several examples from actual industrial processes will be presented including:
- Simple, robust PAT sensors as inline analytical tools
- Optimization and early safety screening of a Grignard reaction (calorimetry)
- Hydrogenations under pressure: from basic to advanced studies with temperature and gas uptake measurement
MultiMax™ is an automated system for parallel synthesis. Individual reaction parameter control including temperature, stirring, dosing, provides the precision and accuracy required for experiments, such as heat flow measurement, where high performance control is crucial to a study's success. The high level of reaction knowledge acquired will enhance chemists' creativity towards safer, cost-effective and environmentally sound processes.